ARG45949
anti-PNKP / PNK antibody
anti-PNKP / PNK antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PNKP / PNK |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PNKP / PNK |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PNKP / PNK. |
| 偶联标记 | Un-conjugated |
| 別名 | PNKP; Polynucleotide Kinase 3'-Phosphatase; Polynucleotide kinase-3'-phosphatase; MCSZ; EIEE10; PNK; 2'; Bifunctional polynucleotide phosphatase/kinase; EC 3.1.3.32; EC 2.7.1.78; AOA4; 3'; DNA 5'-kinase/3'-phosphatase |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 57 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q96T60 Human Bifunctional polynucleotide phosphatase/kinase |
|---|---|
| 基因名称 | PNKP |
| 全名 | Polynucleotide Kinase 3'-Phosphatase |
| 背景介绍 | This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010] |
| 生物功能 | Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. [UniProt] |
| 细胞定位 | Nucleus; Chromosome. [UniProt] |
| 预测分子量 | 57 kDa |
| 翻译后修饰 | Phosphoprotein; Acetylation. [UniProt]. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
-
ARG45949 anti-PNKP / PNK antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45949 anti-PNKP / PNK antibody at 5 μg/ml dilution.
-
ARG45949 anti-PNKP / PNK antibody WB image
Western blot: RT4 stained with ARG45949 anti-PNKP / PNK antibody at 0.5 μg/ml dilution.
-
ARG45949 anti-PNKP / PNK antibody FACS image
Flow Cytometry: U251 stained with ARG45949 anti-PNKP / PNK antibody at 1 µg/10^6 cells dilution.
-
ARG45949 anti-PNKP / PNK antibody WB image
Western blot: Rat thymus stained with ARG45949 anti-PNKP / PNK antibody at 0.5 μg/ml dilution.
-
ARG45949 anti-PNKP / PNK antibody WB image
Western blot: Mouse thymus stained with ARG45949 anti-PNKP / PNK antibody at 0.5 μg/ml dilution.
