ARG45560
anti-PLCD3 antibody
anti-PLCD3 antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PLCD3 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PLCD3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PLCD3. |
| 偶联标记 | Un-conjugated |
| 別名 | PLCD3; Phospholipase C Delta 3; PLCD3; Phospholipase C Delta 3; 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Delta-3; Phosphoinositide Phospholipase C-Delta-3; PLC-Delta-3; EC 3.1.4.11; 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Delta-3; Phospholipase C, Delta 3; Phospholipase C-Delta-3; PLC Delta3; KIAA1964 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 94 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8N3E9 Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 |
|---|---|
| 基因名称 | PLCD3 |
| 全名 | Phospholipase C Delta 3 |
| 背景介绍 | This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008] |
| 生物功能 | Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca2+ from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. [UniProt] |
| 细胞定位 | Cytoplasm, Membrane. [UniProt] |
| 预测分子量 | 89 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45560 anti-PLCD3 antibody ICC/IF image
Immunofluorescence: CACO-2 stained with ARG45560 anti-PLCD3 antibody at 5 μg/ml dilution.
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ARG45560 anti-PLCD3 antibody WB image
Western blot: RT-4 stained with ARG45560 anti-PLCD3 antibody at 0.5 μg/ml dilution.
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ARG45560 anti-PLCD3 antibody FACS image
Flow Cytometry: HL-60 stained with ARG45560 anti-PLCD3 antibody at 1 µg/10^6 cells dilution.
