ARG43842
anti-PLCD3 antibody
anti-PLCD3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Goat Polyclonal antibody recognizes PLCD3 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Pig |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PLCD3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the internal region of Human PLCD3. |
| 偶联标记 | Un-conjugated |
| Protein Full name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 |
| 別名 | PLCD3; Phospholipase C Delta 3; 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Delta-3; Phosphoinositide Phospholipase C-Delta-3; PLC-Delta-3; EC 3.1.4.11; 1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Delta-3; Phospholipase C, Delta 3; Phospholipase C-Delta-3; PLC Delta3; KIAA1964 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8N3E9 Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 |
|---|---|
| 基因名称 | PLCD3 |
| 全名 | Phospholipase C Delta 3 |
| 背景介绍 | This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008] |
| 生物功能 | Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca2+ from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. |
| 细胞定位 | Cytoplasm, Membrane |
| 预测分子量 | 89 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (3) Click the Picture to Zoom In
-
ARG43842 anti-PLCD3 antibody IHC-P image
Immunohistochemistry: Human Kidney stained with ARG43842 anti-PLCD3 antibody at 6 µg/ml
-
ARG43842 anti-PLCD3 antibody WB image
Western blot: Caco-2 cell stained with ARG43842 anti-PLCD3 antibody at 3 µg/ml.
-
ARG43842 anti-PLCD3 antibody IHC-P image
Immunohistochemistry: Human Testis stained with ARG43842 anti-PLCD3 antibody at 6 µg/ml
