ARG45947
anti-PLCD1 antibody
anti-PLCD1 antibody for Western blot,Flow cytometry and Human,Mouse,Rat
概述
产品描述 | Rabbit Polyclonal antibody recognizes PLCD1 |
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反应物种 | Hu, Ms, Rat |
应用 | FACS, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PLCD1 |
抗原物种 | Human |
抗原 | Recombinant protein containing to human PLCD1. |
偶联标记 | Un-conjugated |
別名 | Phospholipase C Delta 1; PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1; EC 3.1.4.11; Phosphoinositide phospholipase C-delta-1; Phospholipase C-III; PLC-III; Phospholipase C-delta-1; PLC-delta-1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
实际分子量 | 86 kDa |
属性
形式 | Liquid |
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纯化 | Affinity chromatography purified |
缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | PLCD1 |
全名 | Phospholipase C Delta 1 |
背景介绍 | This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
生物功能 | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. [UniProt] |
细胞定位 | Cytoplasm; plasma membrane. [UniProt] |
预测分子量 | 86 kDa |
翻译后修饰 | Phosphoprotein; Glycoprotein. [UniProt]. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45947 anti-PLCD1 antibody FACS image
Flow Cytometry: 293T stained with ARG45947 anti-PLCD1 antibody at 1 µg/10^6 cells dilution.
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ARG45947 anti-PLCD1 antibody WB image
Western blot: Rat lung stained with ARG45947 anti-PLCD1 antibody at 0.5 μg/ml dilution.
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ARG45947 anti-PLCD1 antibody WB image
Western blot: Mouse lung stained with ARG45947 anti-PLCD1 antibody at 0.5 μg/ml dilution.