ARG45947

anti-PLCD1 antibody

anti-PLCD1 antibody for Western blot,Flow cytometry and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes PLCD1
反应物种 Hu, Ms, Rat
应用 FACS, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 PLCD1
抗原物种 Human
抗原 Recombinant protein containing to human PLCD1.
偶联标记 Un-conjugated
別名 Phospholipase C Delta 1; PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1; EC 3.1.4.11; Phosphoinositide phospholipase C-delta-1; Phospholipase C-III; PLC-III; Phospholipase C-delta-1; PLC-delta-1

应用说明

应用建议
应用 推荐稀释比
FACS1 - 3 µg/10^6 cells
WB0.25-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 86 kDa

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 18799 Mouse PLCD1

GeneID: 24655 Rat PLCD1

GeneID: 5333 Human PLCD1

基因名称 PLCD1
全名 Phospholipase C Delta 1
背景介绍 This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
生物功能 The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. [UniProt]
细胞定位 Cytoplasm; plasma membrane. [UniProt]
预测分子量 86 kDa
翻译后修饰 Phosphoprotein; Glycoprotein. [UniProt]. [UniProt]

检测图片 (3) Click the Picture to Zoom In

  • ARG45947 anti-PLCD1 antibody FACS image

    Flow Cytometry: 293T stained with ARG45947 anti-PLCD1 antibody at 1 µg/10^6 cells dilution.

  • ARG45947 anti-PLCD1 antibody WB image

    Western blot: Rat lung stained with ARG45947 anti-PLCD1 antibody at 0.5 μg/ml dilution.

  • ARG45947 anti-PLCD1 antibody WB image

    Western blot: Mouse lung stained with ARG45947 anti-PLCD1 antibody at 0.5 μg/ml dilution.