ARG56998
anti-PKLR antibody [1E3]
anti-PKLR antibody [1E3] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [1E3] recognizes PKLR |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1E3 |
| 同位型 | IgG1, kappa |
| 靶点名称 | PKLR |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 47-574 of Human PKLR. |
| 偶联标记 | Un-conjugated |
| 別名 | PKR; PKRL; PK1; Pyruvate kinase isozymes L/R; R-type/L-type pyruvate kinase; Pyruvate kinase PKLR; Pyruvate kinase 1; EC 2.7.1.40; RPK; Red cell/liver pyruvate kinase; PKL |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PKLR |
| 全名 | pyruvate kinase, liver and RBC |
| 背景介绍 | The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a key role in glycolysis. [UniProt] |
| 预测分子量 | 62 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG56998 anti-PKLR antibody [1E3] WB image
Western blot: 40 µg of 293T cell lysate stained with ARG56998 anti-PKLR antibody [1E3] at 1:500.
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ARG56998 anti-PKLR antibody [1E3] WB image
Western blot: 40 µg of 1) Balb-3T3 cell lysate, 2) HeLa cell lysate, 3) Raji cell lysate, 4) K562 cell lysate, 5) A549 cell lysate. stained with ARG56998 anti-PKLR antibody [1E3] at 1:500.
