ARG64261
anti-PIWI / HIWI antibody
anti-PIWI / HIWI antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes PIWI / HIWI |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Dog, Pig |
| 应用 | IHC-P |
| 特异性 | This antibody is expected to recognise both reported isoforms (NP_004755.2; NP_001177900.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PIWI / HIWI |
| 抗原物种 | Human |
| 抗原 | C-SNRKDKYDAIKKY |
| 偶联标记 | Un-conjugated |
| 別名 | Piwi-like protein 1; HIWI; MIWI; CT80.1; PIWI |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 99 kDa |
| 翻译后修饰 | Arginine methylation by PRMT5 is required for the interaction with Tudor domain-containing protein (TDRD1, TDRKH/TDRD2, RNF17/TDRD4, TDRD6, TDRD7 and TDRD9) and subsequent localization to the meiotic nuage, also named P granule. |
检测图片 (1) Click the Picture to Zoom In
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ARG64261 anti-PIWI / HIWI antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Testis. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64261 anti-PIWI / HIWI antibody at 4 µg/ml dilution followed by HRP-staining.
