ARG67111
anti-PIK3R5 antibody
anti-PIK3R5 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PIK3R5 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PIK3R5 |
| 抗原物种 | Human |
| 抗原 | Human PIK3R5 Synthesized peptide |
| 偶联标记 | Un-conjugated |
| 別名 | PIK3R5; Phosphoinositide-3-Kinase Regulatory Subunit 5; P101-PI3K; P101; Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Regulatory Subunit; Phosphoinositide 3-Kinase Regulatory Subunit 5; PI3-Kinase P101 Subunit; PtdIns-3-Kinase P101; Protein FOAP-2; Phosphoinositide-3-Kinase, Regulatory Subunit 5; PtdIns-3-Kinase Regulatory Subunit; PI3-Kinase Regulatory Subunit 5; F730038I15Rik; FOAP-2 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 |
Swiss-port # Q5SW28 Mouse Phosphoinositide 3-kinase regulatory subunit 5 Swiss-port # Q8WYR1 Human Phosphoinositide 3-kinase regulatory subunit 5 |
|---|---|
| 基因名称 | PIK3R5 |
| 全名 | Phosphoinositide-3-Kinase Regulatory Subunit 5 |
| 背景介绍 | Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. |
| 生物功能 | Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG. |
| 细胞定位 | Cell membrane, Cytoplasm, Membrane, Nucleus |
| 预测分子量 | 97 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (1) Click the Picture to Zoom In
-
ARG67111 anti-PIK3R5 antibody IHC-P image
Immunohistochemistry: Human colon carcinoma stained with ARG67111 anti-PIK3R5 antibody.
