ARG44046

anti-PIK3R4 / VPS15 antibody

anti-PIK3R4 / VPS15 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes PIK3R4 / VPS15
反应物种 Hu, Ms
应用 IHC-P, IP, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 PIK3R4 / VPS15
抗原物种 Human
抗原 Recombinant fusion of Human PIK3R4 / VPS15.
偶联标记 Un-conjugated
別名 PIK3R4; Phosphoinositide-3-Kinase Regulatory Subunit 4; VPS15; P150; Phosphoinositide 3-Kinase Regulatory Subunit 4; Phosphoinositide 3-Kinase Adaptor Protein; PI3-Kinase Regulatory Subunit 4; PI3-Kinase P150 Subunit; EC 2.7.11.1; Phosphoinositide-3-Kinase, Regulatory Subunit 4, P150; Phosphoinositide-3-Kinase, Regulatory Subunit 4; Phosphatidylinositol 3-Kinase-Associated P150

应用说明

应用建议
应用 推荐稀释比
IHC-P1:100-1:1000
IP1:100-1:500
WB1:500-1:3000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7), 0.025% proclin300 and 20% Glycerol.
抗菌剂 0.025% proclin300
稳定剂 20% Glycerol.
浓度 4.61 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 30849 Human PIK3R4

GeneID: 75669 Mouse PIK3R4

Swiss-port # Q8VD65 Mouse Phosphoinositide 3-kinase regulatory subunit 4

Swiss-port # Q99570 Human Phosphoinositide 3-kinase regulatory subunit 4

基因名称 PIK3R4
全名 Phosphoinositide-3-Kinase Regulatory Subunit 4
背景介绍 Predicted to enable protein serine/threonine kinase activity. Involved in positive regulation of phosphatidylinositol 3-kinase activity; receptor catabolic process; and regulation of cytokinesis. Located in late endosome and microtubule cytoskeleton.
生物功能 Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2.
细胞定位 Cytoplasmic vesicle, Endosome, Membrane
预测分子量 153 kDa
翻译后修饰 Lipoprotein, Myristate, Phosphoprotein

检测图片 (3) Click the Picture to Zoom In

  • ARG44046 anti-PIK3R4 / VPS15 antibody IHC-P image

    Immunohistochemistry: Mouse duodenum stained with ARG44046 anti-PIK3R4 / VPS15 antibody at 1:500 dilution.

  • ARG44046 anti-PIK3R4 / VPS15 antibody WB image

    Western blot: 293T, A431 and HeLa stained with ARG44046 anti-PIK3R4 / VPS15 antibody at 1:1000 dilution.

  • ARG44046 anti-PIK3R4 / VPS15 antibody WB image

    Western blot: Mouse Liver stained with ARG44046 anti-PIK3R4 / VPS15 antibody at 1:1000 dilution.