ARG58964
anti-PIGR antibody
anti-PIGR antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PIGR |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PIGR |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 661-764 of Human PIGR (NP_002635.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Polymeric immunoglobulin receptor; Hepatocellular carcinoma-associated protein TB6; PIgR; Poly-Ig receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | SGC-7901 | ||||||||
| 实际分子量 | 110 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PIGR |
| 全名 | polymeric immunoglobulin receptor |
| 背景介绍 | This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009] |
| 生物功能 | This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. [UniProt] |
| 细胞定位 | Cell membrane, Single-pass type I membrane protein, Secreted. [UniProt] |
| 预测分子量 | 83 kDa |
| 翻译后修饰 | N-glycosylation is not necessary for Ig binding. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG58964 anti-PIGR antibody WB image
Western blot: 25 µg of SGC-7901 cell lysate stained with ARG58964 anti-PIGR antibody at 1:1000 dilution.
