ARG64024
anti-PICK1 antibody
anti-PICK1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes PICK1 |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Cow, Rat, Dog, Pig |
| 应用 | IHC-P, WB |
| 特异性 | Reported variants represent identical protein (NP_036539.1; NP_001034672.1; NP_001034673.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PICK1 |
| 抗原物种 | Human |
| 抗原 | C-HYNKLQADPKQ |
| 偶联标记 | Un-conjugated |
| 別名 | PRKCABP; PRKCA-binding protein; Protein interacting with C kinase 1; Protein kinase C-alpha-binding protein; PICK |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| 研究领域 | Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 47 kDa |
| 翻译后修饰 | Phosphorylation at Thr-82 appears to inhibit the interaction with AMPA receptors. Palmitoylation on Cys-413 is essential for long-term synaptic depression (LTD). |
检测图片 (3) Click the Picture to Zoom In
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ARG64024 anti-PICK1 antibody WB image
Western Blot: mouse brain lysate (35 µg protein in RIPA buffer) stained with ARG64024 anti-PICK1 antibody at 1 µg/ml dilution.
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ARG64024 anti-PICK1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colon tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64024 anti-PICK1 antibody at 5 µg/ml dilution followed by AP-staining.
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ARG64024 anti-PICK1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human prostate tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64024 anti-PICK1 antibody at 5 µg/ml dilution followed by AP-staining.
