ARG66932
anti-PHOX2B antibody [SQab22261]
anti-PHOX2B antibody [SQab22261] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab22261] recognizes PHOX2B |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab22261 |
| 同位型 | IgG |
| 靶点名称 | PHOX2B |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human PHOX2B. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Paired mesoderm homeobox protein 2B |
| 別名 | NBPhox; PHOX2B homeodomain protein; Paired-like homeobox 2B; Neuroblastoma Phox; Paired mesoderm homeobox protein 2B; PMX2B; NBLST2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 30 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Human neuroblastoma tissue |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05%BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q99453 Human Paired mesoderm homeobox protein 2B |
|---|---|
| 基因名称 | PHOX2B |
| 全名 | paired-like homeobox 2b |
| 背景介绍 | The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 32 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66932 anti-PHOX2B antibody [SQab22261] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded sections of Human neuroblastoma tissue stained with ARG66932 anti-PHOX2B antibody [SQab22261]. Antigen Retrieval: Heat tissue section in Tris-EDTA buffer (pH 9.0).
