ARG45175
anti-PHEX antibody
anti-PHEX antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey
概述
产品描述 | Rabbit Polyclonal antibody recognizes PHEX |
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反应物种 | Hu, Ms, Rat, Mk |
应用 | FACS, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PHEX |
抗原物种 | Human |
抗原 | Recombinant protein containing to human PHEX. |
偶联标记 | Un-conjugated |
別名 | PHEX; phosphate regulating endopeptidase homolog X-linked; Phosphate-regulating neutral endopeptidase PHEX; Metalloendopeptidase homolog PEX; Vitamin D-resistant hypophosphatemic rickets protein; X-linked hypophosphatemia protein; HYP; PHEX; PEX |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
实际分子量 | 86 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 |
Swiss-port # P70669 Mouse Metalloendopeptidase homolog PEX Swiss-port # P78562 Human Phosphate-regulating neutral endopeptidase |
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基因名称 | PHEX |
全名 | phosphate regulating endopeptidase homolog X-linked |
背景介绍 | The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
生物功能 | Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity . [UniProt] |
细胞定位 | Cell membrane. [UniProt] |
预测分子量 | 86 kDa |
翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45175 anti-PHEX antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45175 anti-PHEX antibody at 1 μg/ml dilution.
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ARG45175 anti-PHEX antibody WB image
Western blot: HEK293 stained with ARG45175 anti-PHEX antibody at 0.5 μg/ml dilution.
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ARG45175 anti-PHEX antibody FACS image
Flow Cytometry: U87 stained with ARG45175 anti-PHEX antibody at 1 µg/10^6 cells dilution.
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ARG45175 anti-PHEX antibody WB image
Western blot: Rat ovary, rat kidney, and NRK stained with ARG45175 anti-PHEX antibody at 0.5 μg/ml dilution.
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ARG45175 anti-PHEX antibody WB image
Western blot: Mouse ovary and mouse kidney stained with ARG45175 anti-PHEX antibody at 0.5 μg/ml dilution.
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ARG45175 anti-PHEX antibody WB image
Western blot: Monkey kidney and COS-7 stained with ARG45175 anti-PHEX antibody at 0.5 μg/ml dilution.