ARG45175

anti-PHEX antibody

anti-PHEX antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey

概述

产品描述 Rabbit Polyclonal antibody recognizes PHEX
反应物种 Hu, Ms, Rat, Mk
应用 FACS, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 PHEX
抗原物种 Human
抗原 Recombinant protein containing to human PHEX.
偶联标记 Un-conjugated
別名 PHEX; phosphate regulating endopeptidase homolog X-linked; Phosphate-regulating neutral endopeptidase PHEX; Metalloendopeptidase homolog PEX; Vitamin D-resistant hypophosphatemic rickets protein; X-linked hypophosphatemia protein; HYP; PHEX; PEX

应用说明

应用建议
应用 推荐稀释比
FACS1 - 3 µg/10^6 cells
IHC-P0.5-1 μg/ml
WB0.25-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 86 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose.
抗菌剂 0.05% Sodium azide
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 18675 Mouse PHEX

GeneID: 5251 Human PHEX

Swiss-port # P70669 Mouse Metalloendopeptidase homolog PEX

Swiss-port # P78562 Human Phosphate-regulating neutral endopeptidase

基因名称 PHEX
全名 phosphate regulating endopeptidase homolog X-linked
背景介绍 The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
生物功能 Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity . [UniProt]
细胞定位 Cell membrane. [UniProt]
预测分子量 86 kDa
翻译后修饰 Disulfide bond; Glycoprotein. [UniProt]

检测图片 (6) Click the Picture to Zoom In

  • ARG45175 anti-PHEX antibody IHC-P image

    Immunohistochemistry: Human lung cancer stained with ARG45175 anti-PHEX antibody at 1 μg/ml dilution.

  • ARG45175 anti-PHEX antibody WB image

    Western blot: HEK293 stained with ARG45175 anti-PHEX antibody at 0.5 μg/ml dilution.

  • ARG45175 anti-PHEX antibody FACS image

    Flow Cytometry: U87 stained with ARG45175 anti-PHEX antibody at 1 µg/10^6 cells dilution.

  • ARG45175 anti-PHEX antibody WB image

    Western blot: Rat ovary, rat kidney, and NRK stained with ARG45175 anti-PHEX antibody at 0.5 μg/ml dilution.

  • ARG45175 anti-PHEX antibody WB image

    Western blot: Mouse ovary and mouse kidney stained with ARG45175 anti-PHEX antibody at 0.5 μg/ml dilution.

  • ARG45175 anti-PHEX antibody WB image

    Western blot: Monkey kidney and COS-7 stained with ARG45175 anti-PHEX antibody at 0.5 μg/ml dilution.