ARG46368
anti-PHC3 antibody
anti-PHC3 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PHC3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PHC3 |
| 抗原物种 | Human |
| 抗原 | A 19 amino acid synthetic peptide within the last 50 amino acids of human PHC3. |
| 偶联标记 | Un-conjugated |
| 別名 | polyhomeotic homolog 3 (Drosophila); PHC3; EDR3; HPH3; EDR3; PH3; Polyhomeotic-like protein 3; Early development regulatory protein 3; hPH3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 120 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -418°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PHC3 |
| 全名 | polyhomeotic homolog 3 (Drosophila) |
| 背景介绍 | Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Located in nucleoplasm. Part of PRC1 complex. [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 109 kDa |
| 翻译后修饰 | Phosphoprotein; Isopeptide bond; Ubl conjugation. [UniProt] |
