ARG10814
anti-PGCB antibody
anti-PGCB antibody for Confocal microscopy (Confocal),Dot blot,ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PGCB |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PGCB |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C-terminus of PGCB protein. |
| 偶联标记 | Un-conjugated |
| 別名 | ANPRB; AMDM; GUCY2B; ECDM; Atrial natriuretic peptide receptor 2; NPR-B; SNSK; NPRBi; Guanylate cyclase B; NPRB; ANPb; Atrial natriuretic peptide receptor type B; GUC2B; EC 4.6.1.2; GC-B; ANPR-B; ANP-B |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 30% Glycerol and 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NPR2 |
| 全名 | natriuretic peptide receptor 2 |
| 背景介绍 | This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. [UniProt] |
| 预测分子量 | 117 kDa |
| 翻译后修饰 | Phosphorylated (PubMed:26980729). Phosphorylation of the protein kinase-like domain is required for full activation by CNP (By similarity). Glycosylated. |
检测图片 (2) Click the Picture to Zoom In
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ARG10814 anti-PGCB antibody IHC image
Immunohistochemistry: Thin section of Mouse nose tissue stained with ARG10814 anti-PGCB antibody (red). Green: Grueneberg ganglion neurons. Blue: Nuclei. Staining is found on blood vessel walls.
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ARG10814 anti-PGCB antibody WB image
Western blot: Recombinant PGCB protein stained with ARG10814 anti-PGCB antibody at 1:500 dilution.
