ARG45119
anti-PGAM5 antibody
anti-PGAM5 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PGAM5 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PGAM5 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding Human PGAM5. |
| 偶联标记 | Un-conjugated |
| 別名 | PGAM5; PGAM Family Member 5, Mitochondrial Serine/Threonine Protein Phosphatase; Phosphoglycerate Mutase Family Member 5; Bcl-XL-Binding Protein V68; BXLBv68; PGAM Family Member 5, Serine/Threonine Protein Phosphatase, Mitochondrial; Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial; MGC5352; EC 3.1.3.16 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.05% Proclin300 and 50% Glycerol. |
| 抗菌剂 | 0.05% Proclin300 |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PGAM5 |
| 全名 | PGAM Family Member 5, Mitochondrial Serine/Threonine Protein Phosphatase |
| 背景介绍 | Enables GTPase activator activity and protein serine/threonine phosphatase activity. Involved in necroptotic process. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Nov 2024] |
| 生物功能 | Regulates necroptosis by acting as a RIPK3 target and recruiting the RIPK1-RIPK3-MLKL necrosis 'attack' complex to mitochondria. [Uniprot] |
| 细胞定位 | Membrane, Mitochondrion, Mitochondrion inner membrane, Mitochondrion outer membrane. [Uniprot] |
| 预测分子量 | 32 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein. [Uniprot] |
检测图片 (3) Click the Picture to Zoom In
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ARG45119 anti-PGAM5 antibody IHC-P image
Immunohistochemistry: Human colon carcinoma stained with ARG45119 anti-PGAM5 antibody at 1:20 dilution.
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ARG45119 anti-PGAM5 antibody ICC/IF image
Immunofluorescence: MCF7 stained with ARG45119 anti-PGAM5 antibody at 1:20 dilution.
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ARG45119 anti-PGAM5 antibody WB image
Western blot: HeLa, A549 and MCF7 stained with ARG45119 anti-PGAM5 antibody at 1:500 dilution.
