ARG57158
anti-PGAM2 antibody [5A7]
anti-PGAM2 antibody [5A7] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [5A7] recognizes PGAM2 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 5A7 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | PGAM2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-253 of Human PGAM2 |
| 偶联标记 | Un-conjugated |
| 別名 | PGAM-M; Phosphoglycerate mutase isozyme M; EC 3.1.3.13; PGAMM; GSD10; BPG-dependent PGAM 2; Phosphoglycerate mutase 2; EC 5.4.2.11; EC 5.4.2.4; Muscle-specific phosphoglycerate mutase |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PGAM2 |
| 全名 | phosphoglycerate mutase 2 (muscle) |
| 背景介绍 | Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. [provided by RefSeq, Sep 2009] |
| 生物功能 | Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. [UniProt] |
| 预测分子量 | 29 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG57158 anti-PGAM2 antibody [5A7] WB image
Western blot: 50 ng of 1) Recombnant protein, 40 µg of 2) HeLa, 3) HepG2, 4) 293T, 5) Jurkat, 6) NIH3T3, 7) A549, and 8) MCF7 cell lysates stained with ARG57158 anti-PGAM2 antibody [5A7] at 1:1000.
