ARG54874
anti-PFKP antibody
anti-PFKP antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cancer antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PFKP |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PFKP |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 754-784 (C-terminus) of Human PFKP. |
| 偶联标记 | Un-conjugated |
| 別名 | Phosphohexokinase; PFK-C; EC 2.7.1.11; 6-phosphofructokinase type C; Phosphofructo-1-kinase isozyme C; ATP-PFK; ATP-dependent 6-phosphofructokinase, platelet type; PFK-P; PFKF |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | T47D |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q01813 Human ATP-dependent 6-phosphofructokinase, platelet type |
|---|---|
| 基因名称 | PFKP |
| 全名 | phosphofructokinase, platelet |
| 背景介绍 | The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM, Mar 2008] |
| 生物功能 | Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. [UniProt] |
| 细胞定位 | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03184}. |
| 产品亮点 | Related products: Anti-Rabbit IgG secondary antibodies; Related news: Vascular development is regulated by FGF-dependent metabolic control |
| 研究领域 | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 86 kDa |
| 翻译后修饰 | GlcNAcylation decreases enzyme activity. |
检测图片 (2) Click the Picture to Zoom In
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ARG54874 anti-PFKP antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human breast carcinoma tissue stained with ARG54874 anti-PFKP antibody.
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ARG54874 anti-PFKP antibody WB image
Western blot: 35 µg of T47D cell lysate stained with ARG54874 anti-PFKP antibody.
