ARG44722
anti-PFKM antibody
anti-PFKM antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes PFKM |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | PFKM |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | PFK-A; 6-phosphofructokinase type A; PPP1R122; PFKX; ATP-dependent 6-phosphofructokinase, muscle type; EC 2.7.1.11; Phosphofructo-1-kinase isozyme A; PFK1; ATP-PFK; GSD7; PFK-1; Phosphohexokinase; PFK-M; PFKA |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P08237 Human ATP-dependent 6-phosphofructokinase, muscle type |
|---|---|
| 基因名称 | PFKM |
| 全名 | phosphofructokinase, muscle |
| 背景介绍 | Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009] |
| 生物功能 | Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 85 kDa |
| 翻译后修饰 | GlcNAcylation decreases enzyme activity. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG44722 anti-PFKM antibody IHC-P image
Immunohistochemistry: Human skeletal muscle stained with ARG44722 anti-PFKM antibody at 5 µg/mL dilution.
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ARG44722 anti-PFKM antibody WB image
Western blot: SH-SY5Y stained with ARG44722 anti-PFKM antibody at 1 µg/mL dilution.
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ARG44722 anti-PFKM antibody IP image
Immunoprecipitation: SH-SY5Y lysate immunoprecipitated with 2.5 µg of ARG44722 anti-PFKM antibody.
