ARG66579
anti-PFKFB2 phospho (Ser483) antibody
anti-PFKFB2 phospho (Ser483) antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PFKFB2 phospho (Ser483) |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PFKFB2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated phosphospecific peptide around Ser483 of Human PFKFB2. |
| 偶联标记 | Un-conjugated |
| 別名 | 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; 6PF-2-K/Fru-2,6-P2ase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; PFK-2/FBPase-2; PFK/FBPase 2; EC 3.1.3.46; EC 2.7.1.105 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PFKFB2 |
| 全名 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| 背景介绍 | The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Synthesis and degradation of fructose 2,6-bisphosphate. [UniProt] |
| 预测分子量 | 58 kDa |
| 翻译后修饰 | Phosphorylation by AMPK stimulates activity. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG66579 anti-PFKFB2 phospho (Ser483) antibody WB image
Western blot: HeLa, SP2/0 and H9C2 cells. These cells treated with H2O2 and stained with ARG66579 anti-PFKFB2 phospho (Ser483) antibody.
