ARG40799

anti-PFDN5 antibody

anti-PFDN5 antibody for ICC/IF,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes PFDN5
反应物种 Hu, Ms, Rat
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 PFDN5
抗原物种 Human
抗原 Recombinant fusion protein corresponding to aa. 1-154 of Human PFDN5 (NP_002615.2).
偶联标记 Un-conjugated
別名 PFD5; C-Myc-binding protein Mm-1; MM1; MM-1; Myc modulator 1; Prefoldin subunit 5

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
WB1:200 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Raji
实际分子量 15 kDa

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 5204 Human PFDN5

GeneID: 56612 Mouse PFDN5

Swiss-port # Q99471 Human Prefoldin subunit 5

Swiss-port # Q9WU28 Mouse Prefoldin subunit 5

基因名称 PFDN5
全名 prefoldin subunit 5
背景介绍 This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
生物功能 Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC. [UniProt]
细胞定位 Isoform 1: Nucleus. Isoform 2: Cytoplasm. Isoform 3: Nucleus. [UniProt]
预测分子量 17 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG40799 anti-PFDN5 antibody WB image

    Western blot: 25 µg of Raji cell lysate stained with ARG40799 anti-PFDN5 antibody at 1:3000 dilution.