ARG40799
anti-PFDN5 antibody
anti-PFDN5 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
产品描述 | Rabbit Polyclonal antibody recognizes PFDN5 |
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反应物种 | Hu, Ms, Rat |
应用 | ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PFDN5 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 1-154 of Human PFDN5 (NP_002615.2). |
偶联标记 | Un-conjugated |
別名 | PFD5; C-Myc-binding protein Mm-1; MM1; MM-1; Myc modulator 1; Prefoldin subunit 5 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Raji | ||||||
实际分子量 | 15 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | PFDN5 |
全名 | prefoldin subunit 5 |
背景介绍 | This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
生物功能 | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC. [UniProt] |
细胞定位 | Isoform 1: Nucleus. Isoform 2: Cytoplasm. Isoform 3: Nucleus. [UniProt] |
预测分子量 | 17 kDa |
检测图片 (1) Click the Picture to Zoom In