ARG45713
anti-PERM1 antibody
anti-PERM1 antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PERM1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PERM1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PERM1. |
| 偶联标记 | Un-conjugated |
| 別名 | PERM1; PPARGC1 And ESRR Induced Regulator, Muscle 1; C1orf170; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1 And Estrogen-Related Receptor-Induced Regulator In Muscle 1; PGC-1 And ERR-Induced Regulator In Muscle Protein 1; PPARGC1 And ESRR-Induced Regulator In Muscle 1; RP11-54O7.8; MGC13275; PGC-1- And ERR-Induced Regulator In Muscle 1; PGC-1 And ERR-Induced Regulator In Muscle 1; Chromosome 1 Open Reading Frame 170 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 75 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q5SV97 Human PGC-1 and ERR-induced regulator in muscle protein 1 |
|---|---|
| 基因名称 | PERM1 |
| 全名 | PPARGC1 And ESRR Induced Regulator, Muscle 1 |
| 背景介绍 | Involved in response to muscle activity. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Regulates the expression of selective PPARGC1A/B and ESRRA/B/G target genes with roles in glucose and lipid metabolism, energy transfer, contractile function, muscle mitochondrial biogenesis and oxidative capacity. Required for the efficient induction of MT-CO2, MT-CO3, COX4I1, TFB1M, TFB2M, POLRMT and SIRT3 by PPARGC1A. Positively regulates the PPARGC1A/ESRRG-induced expression of CKMT2, TNNI3 and SLC2A4 and negatively regulates the PPARGC1A/ESRRG-induced expression of PDK4. . [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus. [UniProt] |
| 预测分子量 | 81 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG45713 anti-PERM1 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45713 anti-PERM1 antibody at 5 μg/ml dilution.
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ARG45713 anti-PERM1 antibody WB image
Western blot: MCF-7 stained with ARG45713 anti-PERM1 antibody at 0.5 μg/ml dilution.
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ARG45713 anti-PERM1 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG45713 anti-PERM1 antibody at 1 µg/10^6 cells dilution.
