ARG44451
anti-PELI2 / Pellino2 antibody
anti-PELI2 / Pellino2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PELI2 / Pellino2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PELI2 / Pellino2 |
| 抗原物种 | Human |
| 抗原 | Human PELI2 / Pellino2 recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | PELI2; Pellino E3 Ubiquitin Protein Ligase Family Member 2; RING-Type E3 Ubiquitin Transferase Pellino Homolog 2; E3 Ubiquitin-Protein Ligase Pellino Homolog 2; Pellino-2; Pellino (Drosophila) Homolog 2; Pellino Homolog 2 (Drosophila); Protein Pellino Homolog 2; Pellino Homolog 2 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8BST6 Mouse E3 ubiquitin-protein ligase pellino homolog 2 Swiss-port # Q9HAT8 Human E3 ubiquitin-protein ligase pellino homolog 2 |
|---|---|
| 基因名称 | PELI2 |
| 全名 | Pellino E3 Ubiquitin Protein Ligase Family Member 2 |
| 背景介绍 | Predicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase activity. Acts upstream of or within positive regulation of MAPK cascade and positive regulation of protein phosphorylation. Predicted to be located in membrane. |
| 生物功能 | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. |
| 预测分子量 | 46 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (6) Click the Picture to Zoom In
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ARG44451 anti-PELI2 / Pellino2 antibody IHC-P image
Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG44451 anti-PELI2 / Pellino2 antibody at 2 μg/mL dilution.
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ARG44451 anti-PELI2 / Pellino2 antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG44451 anti-PELI2 / Pellino2 antibody at 5 μg/mL dilution.
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ARG44451 anti-PELI2 / Pellino2 antibody WB image
Western blot: Raji and Ramos stained with ARG44451 anti-PELI2 / Pellino2 antibody at 0.5 μg/mL dilution.
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ARG44451 anti-PELI2 / Pellino2 antibody FACS image
Flow Cytometry: THP-1 stained with ARG44451 anti-PELI2 / Pellino2 antibody at 1 μg/10^6 cells dilution.
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ARG44451 anti-PELI2 / Pellino2 antibody WB image
Western blot: Rat spleen and Rat testis stained with ARG44451 anti-PELI2 / Pellino2 antibody at 0.5 μg/mL dilution.
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ARG44451 anti-PELI2 / Pellino2 antibody WB image
Western blot: Mouse testis stained with ARG44451 anti-PELI2 / Pellino2 antibody at 0.5 μg/mL dilution.
