ARG43915

anti-PDXP antibody

anti-PDXP antibody for ELISA,Flow cytometry,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes PDXP
反应物种 Hu, Ms, Rat
应用 ELISA, FACS, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 PDXP
抗原物种 Human
抗原 Human PDXP recombinant protein
表达系统 E.coli
偶联标记 Un-conjugated
Protein Full name Chronophin
別名 PDXP; Pyridoxal Phosphatase; CIN; Chronophin; DJ37E16.5; Pyridoxal (Pyridoxine, Vitamin B6) Phosphatase; Pyridoxal Phosphate Phosphatase; PLP Phosphatase; EC 3.1.3.74; FLJ32703; PLP; Testicular Secretory Protein Li 36; EC 3.1.3.16; EC 3.1.3; PLPP

应用说明

应用建议
应用 推荐稀释比
ELISA0.1-0.5 µg/ml
FACS1-3 µg/1x10^6 cells
WB0.25-0.5 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified with Immunogen.
缓冲液 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 57026 Human PDXP

GeneID: 57028 Mouse PDXP

Swiss-port # P60487 Mouse Pyridoxal phosphate phosphatase

Swiss-port # Q96GD0 Human Pyridoxal phosphate phosphatase

基因名称 PDXP
全名 Pyridoxal Phosphatase
背景介绍 Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP.
生物功能 Also functions as a protein serine phosphatase that specifically dephosphorylates 'Ser-3' in proteins of the actin-depolymerizing factor (ADF)/cofilin family like CFL1 and DSTN. Thereby, regulates cofilin-dependent actin cytoskeleton reorganization, being required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phosphothreonines in LIMK1. Does not dephosphorylate peptides containing phosphotyrosine.
细胞定位 Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane
预测分子量 32 kDa

检测图片 (4) Click the Picture to Zoom In

  • ARG43915 anti-PDXP antibody WB image

    Western blot: SH-SY5Y stained with ARG43915 anti-PDXP antibody at 0.5 μg/mL dilution.

  • ARG43915 anti-PDXP antibody FACS image

    Flow Cytometry: HEL cells stained with ARG43915 anti-PDXP antibody (blue) at 1 μg/1x10^6 cells dilution.

  • ARG43915 anti-PDXP antibody WB image

    Western blot: Rat brain stained with ARG43915 anti-PDXP antibody at 0.5 μg/mL dilution.

  • ARG43915 anti-PDXP antibody WB image

    Western blot: Mouse brain stained with ARG43915 anti-PDXP antibody at 0.5 μg/mL dilution.