ARG43888
anti-PDS5B antibody
anti-PDS5B antibody for ELISA,Flow cytometry,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PDS5B |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ELISA, FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PDS5B |
| 抗原物种 | Human |
| 抗原 | Human PDS5B recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Sister chromatid cohesion protein PDS5 homolog B |
| 別名 | PDS5B; PDS5 Cohesin Associated Factor B; AS3; Androgen-Induced Proliferation Inhibitor; KIAA0979; CG008; APRIN |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q4VA53 Mouse Sister chromatid cohesion protein PDS5 homolog B Swiss-port # Q9NTI5 Human Sister chromatid cohesion protein PDS5 homolog B |
|---|---|
| 基因名称 | PDS5B |
| 全名 | PDS5 Cohesin Associated Factor B |
| 背景介绍 | This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. |
| 生物功能 | Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells. |
| 细胞定位 | Nucleus |
| 预测分子量 | 165 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (3) Click the Picture to Zoom In
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ARG43888 anti-PDS5B antibody WB image
Western blot: MOLT-4 stained with ARG43888 anti-PDS5B antibody at 0.25 μg/mL dilution.
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ARG43888 anti-PDS5B antibody FACS image
Flow Cytometry: PC-3 cells stained withARG43888 anti-PDS5B antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43888 anti-PDS5B antibody WB image
Western blot: Mouse brain stained with ARG43888 anti-PDS5B antibody at 0.25 μg/mL dilution.
