anti-PDE3A antibody

anti-PDE3A antibody for Confocal microscopy (Confocal),Dot blot,ELISA,Fluorescence Resonance Energy Transfer,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat,Monkey,Xenopus

publication_link 参考文献1


产品描述 Rabbit Polyclonal antibody recognizes PDE3A
反应物种 Hu, Ms, Rat, Mk, Xenopus
应用 Confocal, Dot, ELISA, FRET, ICC/IF, IHC-P, IP, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 PDE3A
抗原物种 Human
抗原 Synthetic peptide selective only for PDE3A variants.
偶联标记 Un-conjugated
別名 EC; Cyclic GMP-inhibited phosphodiesterase A; CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB; cGMP-inhibited 3',5'-cyclic phosphodiesterase A


应用 推荐稀释比
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Affinity purified.
缓冲液 Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 30% Glycerol and 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 50678 Rat PDE3A

GeneID: 5139 Human PDE3A

GeneID: 54611 Mouse PDE3A

基因名称 PDE3A
全名 phosphodiesterase 3A, cGMP-inhibited
背景介绍 This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
生物功能 Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. [UniProt]
预测分子量 125 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG10796 anti-PDE3A antibody ICC/IF image

    Immunofluorescence: Ice-cold Acetone/Methanol (1:1) fixed (5 min) cultured rat smooth muscle cells stained with ARG10796 anti-PDE3A antibody (red) at 1:100 dilution. Nuclei were counterstained with DAPI (blue).

  • ARG10796 anti-PDE3A antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human ovarian medulla tissue stained with ARG10796 anti-PDE3A antibody at 1:100 dilution.


Electroacupuncture promotes the gastrointestinal motility of diabetic mice by CNP/NPR-B-cGMP and PDE3A-cGMP signaling.

WB / Mouse

An Jing et al.
Neurogastroenterol Motil.,  (2019)