ARG10793
anti-PDE1C antibody
anti-PDE1C antibody for Confocal microscopy (Confocal),Dot blot,ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PDE1C |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PDE1C |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide from Human PDE1C. |
| 偶联标记 | Un-conjugated |
| 別名 | Hcam3; cam-PDE 1C; EC 3.1.4.17; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; hCam-3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 30% Glycerol and 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PDE1C |
| 全名 | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| 背景介绍 | Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009] |
| 生物功能 | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. [UniProt] |
| 预测分子量 | PDE1C1: 76 kDa PDE1C2: 70 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG10793 anti-PDE1C antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human ovarian medulla tissue stained with ARG10793 anti-PDE1C antibody at 1:1500 dilution.
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ARG10793 anti-PDE1C antibody WB image
Western blot: Recombinant PDE1C2 and PDE1C1 protein stained with ARG10793 anti-PDE1C antibody at 1:500 dilution.
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ARG10793 anti-PDE1C antibody WB image
Western blot: 50 µg of Rat brain on SDS-PAGE stained with ARG10793 anti-PDE1C antibody at 1:250 dilution.
