ARG10792
anti-PDE1B antibody
anti-PDE1B antibody for Confocal microscopy (Confocal),Dot blot,ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PDE1B |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PDE1B |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide from Human PDE1B protein. |
| 偶联标记 | Un-conjugated |
| 別名 | Cam-PDE 1B; EC 3.1.4.17; 63 kDa Cam-PDE; PDES1B; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; PDE1B1; HEL-S-79p |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 30% Glycerol and 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PDE1B |
| 全名 | phosphodiesterase 1B, calmodulin-dependent |
| 背景介绍 | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
| 生物功能 | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate. [UniProt] |
| 预测分子量 | 61 kDa. Multiple bands in the 65 - 72 kDa range all believed to be various PDE1B variants. |
检测图片 (2) Click the Picture to Zoom In
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ARG10792 anti-PDE1B antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human ovarian medulla tissue stained with ARG10792 anti-PDE1B antibody at 1:200 dilution.
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ARG10792 anti-PDE1B antibody WB image
Western blot: Recombinant PDE1B protein stained with ARG10792 anti-PDE1B antibody at 1:500 dilution.
