ARG43971
anti-PDCD4 antibody
anti-PDCD4 antibody for ELISA,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PDCD4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PDCD4 |
| 抗原物种 | Human |
| 抗原 | Human PDCD4 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Programmed cell death protein 4 |
| 別名 | PDCD4; Programmed Cell Death 4; H731; Programmed Cell Death 4 (Neoplastic Transformation Inhibitor); Neoplastic Transformation Inhibitor Protein; Programmed Cell Death Protein 4; Nuclear Antigen H731; Protein 197/15a; Nuclear Antigen H731-Like |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PDCD4 |
| 全名 | Programmed Cell Death 4 |
| 背景介绍 | This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. |
| 生物功能 | Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA. |
| 细胞定位 | Cytoplasm, Nucleus |
| 预测分子量 | 52 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein, Ubl conjugation |
检测图片 (3) Click the Picture to Zoom In
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ARG43971 anti-PDCD4 antibody WB image
Western blot: Hela and 293T stained with ARG43971 anti-PDCD4 antibody at 0.5 μg/mL dilution.
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ARG43971 anti-PDCD4 antibody WB image
Western blot: NIH/3T3 stained with ARG43971 anti-PDCD4 antibody at 0.5 μg/mL dilution.
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ARG43971 anti-PDCD4 antibody WB image
Western blot: Rat brain stained with ARG43971 anti-PDCD4 antibody at 0.5 μg/mL dilution.
