ARG64704

anti-PCSK6 antibody

anti-PCSK6 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Cell Biology and Cellular Response antibody

概述

产品描述 Goat Polyclonal antibody recognizes PCSK6
反应物种 Hu
应用 IHC-P
特异性 This antibody is expected to recognize reported isoforms a, b, g and h (NP_002561.1; NP_612192.1; NP_612193.1; NP_612194.1 resp.).
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 PCSK6
抗原物种 Human
抗原 C-YHTFSAHQSRSR
偶联标记 Un-conjugated
別名 Subtilisin/kexin-like protease PACE4; Subtilisin-like proprotein convertase 4; PACE4; Proprotein convertase subtilisin/kexin type 6; Paired basic amino acid cleaving enzyme 4; EC 3.4.21.-; SPC4

应用说明

应用建议
应用 推荐稀释比
IHC-P5 µg/ml
应用说明 IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 5046 Human PCSK6

Swiss-port # P29122 Human Proprotein convertase subtilisin/kexin type 6

背景介绍 The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
研究领域 Cell Biology and Cellular Response antibody
预测分子量 106 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG64704 anti-PCSK6 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64704 anti-PCSK6 antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG64704 anti-PCSK6 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Skeletal Muscle. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64704 anti-PCSK6 antibody at 5 µg/ml dilution followed by AP-staining.