ARG44459
anti-PCMT1 antibody
anti-PCMT1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PCMT1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PCMT1 |
| 抗原物种 | Human |
| 抗原 | Human PCMT1 recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | PCMT1; Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase; Protein-L-Isoaspartate(D-Aspartate) O-Methyltransferase; Protein L-Isoaspartyl/D-Aspartyl Methyltransferase; L-Isoaspartyl Protein Carboxyl Methyltransferase; Protein-Beta-Aspartate Methyltransferase; EC 2.1.1.77; PIMT; Epididymis Secretory Sperm Binding Protein |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P22061 Human Protein-L-isoaspartate(D-aspartate) O-methyltransferase Swiss-port # P22062 Rat Protein-L-isoaspartate(D-aspartate) O-methyltransferase |
|---|---|
| 基因名称 | PCMT1 |
| 全名 | Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase |
| 背景介绍 | This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| 生物功能 | Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins . |
| 细胞定位 | Cytoplasm |
| 预测分子量 | 25 kDa |
| 翻译后修饰 | Acetylation |
检测图片 (5) Click the Picture to Zoom In
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ARG44459 anti-PCMT1 antibody IHC-P image
Immunohistochemistry: Human glioblastoma stained with ARG44459 anti-PCMT1 antibody at 2 μg/mL dilution.
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ARG44459 anti-PCMT1 antibody ICC/IF image
Immunofluorescence: SiHa stained with ARG44459 anti-PCMT1 antibody at 5 μg/mL dilution.
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ARG44459 anti-PCMT1 antibody WB image
Western blot: Hela, Raji and 293T stained with ARG44459 anti-PCMT1 antibody at 0.5 μg/mL dilution.
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ARG44459 anti-PCMT1 antibody WB image
Western blot: Rat testis and Rat brain stained with ARG44459 anti-PCMT1 antibody at 0.5 μg/mL dilution.
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ARG44459 anti-PCMT1 antibody WB image
Western blot: Mouse testis and Mouse brain stained with ARG44459 anti-PCMT1 antibody at 0.5 μg/mL dilution.
