ARG44461
anti-PCDHGC3 antibody
anti-PCDHGC3 antibody for Flow cytometry,Western blot and Human,Rat
概述
产品描述 | Rabbit Polyclonal antibody recognizes PCDHGC3 |
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反应物种 | Hu, Rat |
应用 | FACS, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PCDHGC3 |
抗原物种 | Human |
抗原 | Human PCDHGC3 recombinant protein |
偶联标记 | Un-conjugated |
別名 | PCDHGC3; Protocadherin Gamma Subfamily C, 3; PCDH-GAMMA-C3; PC-43; PCDH2; PC43; Protocadherin Gamma-C3; Protocadherin 43; Cadherin-Like 2; Protocadherin-2; Protocadherin-43; Protocadherin 2; PCDH-Gamma-C3 |
应用说明
应用建议 |
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应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purified with Immunogen. |
缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | PCDHGC3 |
全名 | Protocadherin Gamma Subfamily C, 3 |
背景介绍 | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. |
生物功能 | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
细胞定位 | Cell membrane, Membrane |
预测分子量 | 101 kDa |
翻译后修饰 | Glycoprotein |
检测图片 (3) Click the Picture to Zoom In
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ARG44461 anti-PCDHGC3 antibody WB image
Western blot: 293T and Jurkat stained with ARG44461 anti-PCDHGC3 antibody at 0.5 μg/mL dilution.
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ARG44461 anti-PCDHGC3 antibody FACS image
Flow Cytometry: JK stained with ARG44461 anti-PCDHGC3 antibody at 1 μg/10^6 cells dilution.
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ARG44461 anti-PCDHGC3 antibody WB image
Western blot: C6 stained with ARG44461 anti-PCDHGC3 antibody at 0.5 μg/mL dilution.