ARG44457
anti-PCDHGA2 antibody
anti-PCDHGA2 antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PCDHGA2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PCDHGA2 |
| 抗原物种 | Human |
| 抗原 | Human PCDHGA2 recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | PCDHGA2; Protocadherin Gamma Subfamily A, 2; PCDH-GAMMA-A2; Protocadherin Gamma-A2; PCDH-Gamma-A2 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PCDHGA2 |
| 全名 | Protocadherin Gamma Subfamily A, 2 |
| 背景介绍 | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. |
| 生物功能 | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
| 细胞定位 | Cell membrane, Membrane |
| 预测分子量 | 101 kDa |
| 翻译后修饰 | Glycoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44457 anti-PCDHGA2 antibody WB image
Western blot: MCF-7 and A549 stained with ARG44457 anti-PCDHGA2 antibody at 0.5 μg/mL dilution.
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ARG44457 anti-PCDHGA2 antibody WB image
Western blot: Mouse lung stained with ARG44457 anti-PCDHGA2 antibody at 0.5 μg/mL dilution.
