ARG44456

anti-PCDHB14 antibody

anti-PCDHB14 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes PCDHB14
反应物种 Hu, Ms, Rat
应用 FACS, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 PCDHB14
抗原物种 Human
抗原 Human PCDHB14 recombinant protein
偶联标记 Un-conjugated
別名 PCDHB14; Protocadherin Beta 14; PCDH-BETA14; Protocadherin Beta-14; PCDH-Beta-14

应用说明

应用建议
应用 推荐稀释比
FACS1-3 µg/1x10^6
IHC-P2-5 µg/ml
WB0.25-0.5 µg/ml
应用说明 The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified with Immunogen.
缓冲液 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂 0.05% Sodium azide
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 56122 Human PCDHB14

GeneID: 93885 Mouse PCDHB14

Swiss-port # Q6PB90 Mouse Protocadherin beta-14

Swiss-port # Q9Y5E9 Human Protocadherin beta-14

基因名称 PCDHB14
全名 Protocadherin Beta 14
背景介绍 This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
生物功能 Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
细胞定位 Cell membrane, Membrane
预测分子量 88 kDa
翻译后修饰 Disulfide bond, Glycoprotein

检测图片 (5) Click the Picture to Zoom In

  • ARG44456 anti-PCDHB14 antibody IHC-P image

    Immunohistochemistry: Human appendiceal carcinoid stained with ARG44456 anti-PCDHB14 antibody at 2 μg/mL dilution.

  • ARG44456 anti-PCDHB14 antibody WB image

    Western blot: SH-SY5Y and SiHa stained with ARG44456 anti-PCDHB14 antibody at 0.5 μg/mL dilution.

  • ARG44456 anti-PCDHB14 antibody FACS image

    Flow Cytometry: SH-SY5Y stained with ARG44456 anti-PCDHB14 antibody at 1 μg/10^6 cells dilution.

  • ARG44456 anti-PCDHB14 antibody WB image

    Western blot: C6 and PC-12 stained with ARG44456 anti-PCDHB14 antibody at 0.5 μg/mL dilution.

  • ARG44456 anti-PCDHB14 antibody WB image

    Western blot: ANA-1 stained with ARG44456 anti-PCDHB14 antibody at 0.5 μg/mL dilution.