ARG44379
anti-PCCA antibody
anti-PCCA antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PCCA |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PCCA |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein containing a sequence corresponding to amino acids 449-728 of human PCCA |
| 偶联标记 | Un-conjugated |
| 別名 | PCCA; Propionyl-CoA Carboxylase Subunit Alpha; Propionyl-CoA Carboxylase Alpha Chain, Mitochondrial; Propionyl Coenzyme A Carboxylase, Alpha Polypeptide; EC 6.4.1.3; Propanoyl-CoA:Carbon Dioxide Ligase Alpha Subunit; Propanoyl-CoA:Carbon Dioxide Ligase Subunit Alpha; Propionyl CoA Carboxylase, Alpha Polypeptide; Propionyl-CoA Carboxylase Alpha Subunit; PccA Complementation Group; PCCase Alpha Subunit; PCCase Subunit Alpha |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.01% Thimerosal and 50% Glycerol. |
| 抗菌剂 | 0.01% Thimerosal |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PCCA |
| 全名 | Propionyl-CoA Carboxylase Subunit Alpha |
| 背景介绍 | The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites |
| 细胞定位 | Mitochondrion |
| 预测分子量 | 80 kDa |
| 翻译后修饰 | Acetylation,Phosphoprotein |
检测图片 (5) Click the Picture to Zoom In
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ARG44379 anti-PCCA antibody IHC-P image
Immunohistochemistry: Human liver stained with ARG44379 anti-PCCA antibody at 1:100 dilution.
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ARG44379 anti-PCCA antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG44379 anti-PCCA antibody at 1:100 dilution.
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ARG44379 anti-PCCA antibody WB image
Western blot: Rat kidney stained with ARG44379 anti-PCCA antibody at 1:3000 dilution.
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ARG44379 anti-PCCA antibody IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG44379 anti-PCCA antibody at 1:100 dilution.
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ARG44379 anti-PCCA antibody WB image
Western blot: Mouse liver, Mouse brain and Mouse kidney stained with ARG44379 anti-PCCA antibody at 1:3000 dilution.
