ARG65262
anti-PBX1 antibody
anti-PBX1 antibody for Western blot and Human,Mouse,Rat
Developmental Biology antibody; Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes PBX1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Dog |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PBX1 |
| 抗原物种 | Human |
| 抗原 | C-ATNVSAHGSQANSPS |
| 偶联标记 | Un-conjugated |
| 別名 | Homeobox protein PBX1; Pre-B-cell leukemia transcription factor 1; Homeobox protein PRL |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P40424 Human Pre-B-cell leukemia transcription factor 1 Swiss-port # P41778 Mouse Pre-B-cell leukemia transcription factor 1 |
|---|---|
| 背景介绍 | This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| 研究领域 | Developmental Biology antibody; Gene Regulation antibody |
| 预测分子量 | 47 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG65262 anti-PBX1 antibody WB image
Western Blot: K562 lysate (35 µg protein in RIPA buffer) stained with ARG65262 anti-PBX1 antibody at 0.5 µg/ml dilution.
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ARG65262 anti-PBX1 antibody WB image
Western Blot: Mouse Eye lysate (35 µg protein in RIPA buffer) stained with ARG65262 anti-PBX1 antibody at 0.5 µg/ml dilution.
