ARG43636
anti-PASD1 antibody
anti-PASD1 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PASD1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PASD1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within a.a 280-350 of Human PASD1. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Circadian clock protein PASD1 |
| 別名 | Cancer/testis antigen 63; OX-TES-1; OXTES1; CT63; PAS domain-containing protein 1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 87 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PASD1 |
| 全名 | PAS domain containing 1 |
| 背景介绍 | This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010] |
| 生物功能 | Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body (PubMed:25936801). Acts as a nuclear repressor of the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock components (PubMed:25936801). Inhibits circadian clock function in cancer cells, when overexpressed (PubMed:25936801). [UniProt] |
| 细胞定位 | Nucleus |
| 预测分子量 | Isoform 1: 87 kDa Isoform 2: 73 kDa |
