ARG44446
anti-PARD6B antibody
anti-PARD6B antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PARD6B |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PARD6B |
| 抗原物种 | Human |
| 抗原 | Human PARD6B recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | PARD6B; Par-6 Family Cell Polarity Regulator Beta; PAR-6B; Partitioning Defective 6 Homolog Beta; PAR-6 Beta; PAR6B |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9BYG5 Human Partitioning defective 6 homolog beta Swiss-port # Q9JK83 Mouse Partitioning defective 6 homolog beta |
|---|---|
| 基因名称 | PARD6B |
| 全名 | Par-6 Family Cell Polarity Regulator Beta |
| 背景介绍 | This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. |
| 生物功能 | Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. |
| 细胞定位 | Cell junction, Cell membrane, Cytoplasm, Membrane, Tight junction |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (5) Click the Picture to Zoom In
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ARG44446 anti-PARD6B antibody WB image
Western blot: HeLa and 293T stained with ARG44446 anti-PARD6B antibody at 0.5 μg/mL dilution.
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ARG44446 anti-PARD6B antibody ICC/IF image
Immunofluorescence: A431 stained with ARG44446 anti-PARD6B antibody at 5 μg/mL dilution.
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ARG44446 anti-PARD6B antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44446 anti-PARD6B antibody at 1 μg/10^6 cells dilution.
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ARG44446 anti-PARD6B antibody IHC-P image
Immunohistochemistry: Rat kidney stained with ARG44446 anti-PARD6B antibody at 2 μg/mL dilution.
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ARG44446 anti-PARD6B antibody IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG44446 anti-PARD6B antibody at 2 μg/mL dilution.
