ARG44545
anti-PAM16 antibody
anti-PAM16 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PAM16 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PAM16 |
| 抗原物种 | Human |
| 抗原 | Human PAM16 fusion protein |
| 偶联标记 | Un-conjugated |
| 別名 | PAM16; Presequence Translocase Associated Motor 16; TIMM16; Magmas; Tim16; Mitochondria Associated Protein Involved In Granulocyte Macrophage Colony Stimulating Factor Signal Transduction; Mitochondria-Associated Granulocyte Macrophage CSF-Signaling Molecule; Mitochondrial Import Inner Membrane Translocase Subunit TIM16; Presequence Translocase Associated Motor 16 Homolog; Presequence Translocase-Associated Motor 16 Homolog (S. Cerevisiae); Presequence Translocated-Associated Motor Subunit PAM16; Magmas-Like Protein; CGI-136; SMDMDM; MAGMAS; TIM16 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 14 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 40% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9CQV1 Mouse Mitochondrial import inner membrane translocase subunit TIM16 Swiss-port # Q9Y3D7 Human Mitochondrial import inner membrane translocase subunit TIM16 |
|---|---|
| 基因名称 | PAM16 |
| 全名 | Presequence Translocase Associated Motor 16 |
| 背景介绍 | This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. |
| 生物功能 | Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity. |
| 细胞定位 | Membrane, Mitochondrion, Mitochondrion inner membrane |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44545 anti-PAM16 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44545 anti-PAM16 antibody.
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ARG44545 anti-PAM16 antibody WB image
Western blot: HL-60, Hela, Jurkat and LNCAP stained with ARG44545 anti-PAM16 antibody.
