ARG57008
anti-PAIP2 antibody [1C12]
anti-PAIP2 antibody [1C12] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [1C12] recognizes PAIP2 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1C12 |
| 同位型 | IgG2b |
| 靶点名称 | PAIP2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-127 of Human PAIP2. |
| 偶联标记 | Un-conjugated |
| 別名 | A; PABP-interacting protein 2; Poly; PAIP-2; Polyadenylate-binding protein-interacting protein 2; PAIP2A |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9BPZ3 Human Polyadenylate-binding protein-interacting protein 2 |
|---|---|
| 基因名称 | PAIP2 |
| 全名 | poly(A) binding protein interacting protein 2 |
| 生物功能 | Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. [UniProt] |
| 预测分子量 | 15 kDa |
| 翻译后修饰 | Ubiquitinated, leading to its degradation by the proteasome. |
检测图片 (1) Click the Picture to Zoom In
-
ARG57008 anti-PAIP2 antibody [1C12] WB image
Western blot: 40 µg of HeLa cell lysate stained with ARG57008 anti-PAIP2 antibody [1C12] at 1:1000.
