ARG44372
anti-PAICS / PAIS antibody
anti-PAICS / PAIS antibody for ICC/IF,Western blot and Human,Rat
Disease variant
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PAICS / PAIS |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PAICS / PAIS |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human PAICS |
| 偶联标记 | Un-conjugated |
| 別名 | PAICS; Phosphoribosylaminoimidazole Carboxylase And Phosphoribosylaminoimidazolesuccinocarboxamide Synthase; AIRC; ADE2H1; PAIS; Bifunctional Phosphoribosylaminoimidazole Carboxylase/Phosphoribosylaminoimidazole Succinocarboxamide Synthetase; Phosphoribosylaminoimidazole Carboxylase, Phosphoribosylaminoimidazole Succinocarboxamide Synthetase; ADE2; Phosphoribosylaminoimidazole Carboxylase; Phosphoribosylaminoimidazolesuccinocarboxamide Synthase; Multifunctional Protein ADE2H1; Multifunctional Protein ADE2; SAICAR Synthetase; AIR Carboxylase; PAICSD |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PAICS |
| 全名 | Phosphoribosylaminoimidazole Carboxylase And Phosphoribosylaminoimidazolesuccinocarboxamide Synthase |
| 背景介绍 | This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Bifunctional phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase catalyzing two reactions of the de novo purine biosynthetic pathway. |
| 研究领域 | Disease variant |
| 预测分子量 | 47 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44372 anti-PAICS / PAIS antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44372 anti-PAICS / PAIS antibody at 1:50 dilution.
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ARG44372 anti-PAICS / PAIS antibody WB image
Western blot: Jurkat, 293T, SW620, Raji and HeLa stained with ARG44372 anti-PAICS / PAIS antibody at 1:1000 dilution.
