ARG45446
anti-PAFAH1B2 antibody
anti-PAFAH1B2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PAFAH1B2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PAFAH1B2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PAFAH1B2. |
| 偶联标记 | Un-conjugated |
| 別名 | PAFAH1B2; Platelet Activating Factor Acetylhydrolase 1b Catalytic Subunit 2; Platelet-Activating Factor Acetylhydrolase 1b, Catalytic Subunit 2 (30kDa); Platelet-Activating Factor Acetylhydrolase IB Subunit Alpha2; PAF Acetylhydrolase 30 KDa Subunit; PAF-AH1b Alpha 2 Subunit; PAF-AH 30 KDa Subunit; PAF-AH Subunit Beta; PAFAH Subunit Beta; EC 3.1.1.47 47; Platelet-Activating Factor Acetylhydrolase, Isoform Ib, Beta Subunit 30kDa; Platelet-Activating Factor Acetylhydrolase, Isoform Ib, Subunit 2 (30kDa); Intracellular Platelet-Activating Factor Acetylhydrolase Alpha 2 Subunit; Platelet-Activating Factor Acetylhydrolase IB Subunit Beta; Epididymis Secretory Sperm Binding Protein; Epididymis Secretory Protein Li 303; HEL-S-303; PAFAHB |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 26 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PAFAH1B2 |
| 全名 | Platelet Activating Factor Acetylhydrolase 1b Catalytic Subunit 2 |
| 背景介绍 | Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2014] |
| 生物功能 | Alpha2 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF. The activity and substrate specificity of PAF-AH (I) are affected by its subunit composition. The alpha2/alpha2 homodimer (PAFAH1B2/PAFAH1B2 homodimer) hydrolyzes PAF and 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylethanolamine (AAGPE) more efficiently than 1-O-alkyl-2-acetyl-sn-glycero-3-phosphoric acid (AAGPA). In contrast, the alpha1/alpha2 heterodimer(PAFAH1B3/PAFAH1B3 heterodimer) hydrolyzes AAGPA more efficiently than PAF, but has little hydrolytic activity towards AAGPE. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 26 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45446 anti-PAFAH1B2 antibody WB image
Western blot: HEL stained with ARG45446 anti-PAFAH1B2 antibody at 0.5 μg/ml dilution.
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ARG45446 anti-PAFAH1B2 antibody IHC-P image
Immunohistochemistry: Rat colon stained with ARG45446 anti-PAFAH1B2 antibody at 2 μg/ml dilution.
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ARG45446 anti-PAFAH1B2 antibody IHC-P image
Immunohistochemistry: Mouse colon stained with ARG45446 anti-PAFAH1B2 antibody at 2 μg/ml dilution.
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ARG45446 anti-PAFAH1B2 antibody WB image
Western blot: Mouse testis stained with ARG45446 anti-PAFAH1B2 antibody at 0.5 μg/ml dilution.
