ARG67282

anti-P2Y12 antibody

anti-P2Y12 antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Monoclonal antibody recognizes P2Y12
反应物种 Hu, Ms, Rat
应用 ICC/IF, IP, WB
宿主 Rabbit
克隆 Monoclonal
同位型 IgG,Kappa
靶点名称 P2Y12
偶联标记 Un-conjugated
別名 P2RY12; Purinergic Receptor P2Y12; SP1999; P2Y12; HORK3; Purinergic Receptor P2Y, G-Protein Coupled, 12; P2Y12 Platelet ADP Receptor; ADP-Glucose Receptor; P2Y Purinoceptor 12; P2Y(ADP) ; P2Y(Cyc); P2T(AC) ; P2Y(AC) ; ADPG-R; Putative G-Protein Coupled Receptor; G-Protein Coupled Receptor SP1999; Gi-Coupled ADP Receptor HORK3; Purinergic Receptor P2RY12; P2Y(12)R; BDPLT8

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:200 - 1:1000
IP1:50 - 1:200
WB1:2000 - 1:10000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purification with Protein A
缓冲液 PBS, 0.05% Proclin 300, 50% glycerol and 0.05% BSA
抗菌剂 0.05% Proclin 300
稳定剂 50% glycerol and 0.05% BSA
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 64803 Rat P2RY12

GeneID: 64805 Human P2RY12

GeneID: 70839 Mouse P2RY12

基因名称 P2RY12
全名 Purinergic Receptor P2Y12
背景介绍 The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
生物功能 Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. [UniProt]
预测分子量 39 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG67282 anti-P2Y12 antibody WB image

    Western blot: A549 stained with ARG67282 anti-P2Y12 antibody.

  • ARG67282 anti-P2Y12 antibody WB image

    Western blot: PC-12 stained with ARG67282 anti-P2Y12 antibody.