ARG56276

anti-P2RY4 antibody

anti-P2RY4 antibody for Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes P2RY4
反应物种 Hu, Ms, Rat
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 P2RY4
抗原物种 Human
抗原 Synthetic peptide of Human P2RY4
偶联标记 Un-conjugated
別名 UNR; P2Y purinoceptor 4; P2Y4; P2P; Uridine nucleotide receptor; NRU

应用说明

应用建议
应用 推荐稀释比
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Mouse heart and BxPC-3

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 5030 Human P2RY4

GeneID: 57385 Mouse P2RY4

GeneID: 63843 Rat P2RY4

基因名称 P2RY4
全名 pyrimidinergic receptor P2Y, G-protein coupled, 4
背景介绍 The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. [provided by RefSeq, Jul 2008]
生物功能 Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP. [UniProt]
预测分子量 41 kDa
翻译后修饰 Phosphorylation of Ser-333 and Ser-334 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium activated kinases.

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  • ARG56276 anti-P2RY4 antibody WB image

    Western blot: Mouse heart and BxPC-3 cell lysate stained with ARG56276 anti-P2RY4 antibody.