ARG63434
anti-P114-RHO-GEF / ARHGEF18 antibody
anti-P114-RHO-GEF / ARHGEF18 antibody for Western blot and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes P114-RHO-GEF / ARHGEF18 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize both reported isoforms (NP_056133.2; NP_001124427.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | P114-RHO-GEF / ARHGEF18 |
| 抗原物种 | Human |
| 抗原 | C-SAKEDASKEDVIFF |
| 偶联标记 | Un-conjugated |
| 別名 | 114 kDa Rho-specific guanine nucleotide exchange factor; Septin-associated RhoGEF; SA-RhoGEF; p114RhoGEF; p114-Rho-GEF; Rho guanine nucleotide exchange factor 18; P114-RhoGEF |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6ZSZ5 Human Rho guanine nucleotide exchange factor 18 |
|---|---|
| 背景介绍 | Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 152 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG63434 anti-P114-RHO-GEF / ARHGEF18 antibody WB image
Western blot: 35 µg of Daudi (A) and Caco-2 (B) cell lysates (in RIPA buffer) stained with ARG63434 anti-P114-RHO-GEF / ARHGEF18 antibody at 0.5 µg/ml dilution and incubated at RT for 1 hour.
