ARG40960
anti-Osteocalcin (full length) antibody
anti-Osteocalcin (full length) antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Osteocalcin (full length) |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Osteocalcin (full length) |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 2-32 of Human Osteocalcin. |
| 偶联标记 | Un-conjugated |
| 別名 | OCN; Gamma-carboxyglutamic acid-containing protein; Osteocalcin; OC; Bone Gla protein; BGP |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | MG-63 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BGLAP |
| 全名 | bone gamma-carboxyglutamate (gla) protein |
| 背景介绍 | This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015] |
| 生物功能 | Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 11 kDa |
| 翻译后修饰 | Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
-
ARG40960 anti-Osteocalcin (full length) antibody WB image
Western blot: 20 µg of MG-63 whole cell lysate stained with ARG40960 anti-Osteocalcin (full length) antibody at 1:2000 dilution.
