ARG43969
anti-Opioid Receptor antibody
anti-Opioid Receptor antibody for ELISA,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Opioid Receptor |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Opioid Receptor |
| 抗原物种 | Human |
| 抗原 | Human Opioid Receptor recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Mu-type opioid receptor |
| 別名 | OPRM1; Opioid Receptor Mu 1; MOR1 MOP; Mu Opiate Receptor; Mu-Type Opioid Receptor; Mu Opioid Receptor; M-OR-1; Mu Opioid Receptor HMOR-1a; Opioid Receptor, Mu 1; MOR-1; LMOR; OPRM; HMOP; MO |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | OPRM1 |
| 全名 | Opioid Receptor Mu 1 |
| 背景介绍 | This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. |
| 生物功能 | Variant Asp-40 does not show altered binding affinities for most opioid peptides and alkaloids tested, but it binds beta-endorphin, an endogenous opioid that activates the mu opioid receptor, approximately 3 times more tightly than the most common allelic form. |
| 细胞定位 | Cell membrane, Cell projection, Cytoplasm, Endosome, Membrane |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Lipoprotein, Palmitate, Phosphoprotein, Ubl conjugation |
检测图片 (3) Click the Picture to Zoom In
-
ARG43969 anti-Opioid Receptor antibody WB image
Western blot: SH-SY5Y and K562 stained with ARG43969 anti-Opioid Receptor antibody at 0.5 μg/mL dilution.
-
ARG43969 anti-Opioid Receptor antibody WB image
Western blot: Rat brain and Rat heart stained with ARG43969 anti-Opioid Receptor antibody at 0.5 μg/mL dilution.
-
ARG43969 anti-Opioid Receptor antibody WB image
Western blot: Mouse brain and Mouse heart stained with ARG43969 anti-Opioid Receptor antibody at 0.5 μg/mL dilution.
