ARG42886
anti-OXGR1 / GPR99 antibody
anti-OXGR1 / GPR99 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes OXGR1 / GPR99 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | OXGR1 / GPR99 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human OXGR1 / GPR99. |
| 偶联标记 | Un-conjugated |
| 別名 | G-protein coupled receptor 99; P2Y-like nucleotide receptor; G-protein coupled receptor 80; P2Y purinoceptor 15; 2-oxoglutarate receptor 1; P2Y-like GPCR; P2RY15; aKGR; Alpha-ketoglutarate receptor 1; P2Y15; GPR99; GPR80 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HeLa | ||||||||
| 实际分子量 | ~ 38 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | OXGR1 |
| 全名 | oxoglutarate (alpha-ketoglutarate) receptor 1 |
| 背景介绍 | This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016] |
| 生物功能 | Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity). [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 38 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG42886 anti-OXGR1 / GPR99 antibody WB image
Western blot: HeLa cell lysate stained with ARG42886 anti-OXGR1 / GPR99 antibody at 1:1000 dilution.
