ARG67253
anti-OVOL2 antibody [SQab30371]
anti-OVOL2 antibody [SQab30371] for IHC-Formalin-fixed paraffin-embedded sections and Human
. [Uniprot]
概述
| 产品描述 | Rabbit Monoclonal antibody [SQab30371] recognizes OVOL2. |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30371 |
| 同位型 | IgG |
| 靶点名称 | OVOL2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to Human OVOL2. |
| 偶联标记 | Un-conjugated |
| 別名 | OVOL2; Ovo Like Zinc Finger 2; Zinc Finger Protein 339; ZNF339; CHED; Corneal Endothelial Dystrophy 1 (Autosomal Dominant); Transcription Factor Ovo-Like 2; BA504H3.3; HOVO2; CHED1; Ovo-Like 2 (Drosophila); EUROIMAGE566589; CHED2; PPCD1; HOvo2 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | OVOL2 |
| 全名 | Ovo Like Zinc Finger 2 |
| 背景介绍 | This gene encodes a member of the evolutionarily conserved ovo-like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N- and C-terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion, impaired vascularization, and heart anomalies. In humans, allelic variants of this gene have been associated with posterior polymorphous corneal dystrophy. [provided by RefSeq, Apr 2016] |
| 生物功能 | Plays dual functions in thermogenesis and adipogenesis to maintain energy balance. Essential for brown/beige adipose tissue-mediated thermogenesis, is necessary for the development of brown adipocytes. In white adipose tissues, limits adipogenesis by blocking CEBPA binding to its transcriptional targets and inhibiting its transcription factor activity. [Uniprot] |
| 细胞定位 | Nucleus. [Uniprot] |
| 产品亮点 | . [Uniprot] |
| 研究领域 | . [Uniprot] |
| 预测分子量 | 30 kDa |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
检测图片 (2) Click the Picture to Zoom In
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ARG67253 anti-OVOL2 antibody [SQab30371] IHC-P image
Immunohistochemistry: Human Colon cancer stained with ARG67253 anti-OVOL2 antibody [SQab30371] at 1:100 dilution.
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ARG67253 anti-OVOL2 antibody [SQab30371] IHC-P image
Immunohistochemistry: Human Colon cancer stained with ARG67253 anti-OVOL2 antibody [SQab30371] at 1:100 dilution.
