ARG58999

anti-OTC / Ornithine Carbamoyltransferase antibody

anti-OTC / Ornithine Carbamoyltransferase antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes OTC / Ornithine Carbamoyltransferase
反应物种 Hu
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 OTC / Ornithine Carbamoyltransferase
抗原物种 Human
抗原 KLH-conjugated synthetic peptide corresponding to aa. 71-98 of Human OTC / Ornithine Carbamoyltransferase.
偶联标记 Un-conjugated
別名 Ornithine transcarbamylase; OCTD; EC 2.1.3.3; Ornithine carbamoyltransferase, mitochondrial; OTCase

应用说明

应用建议
应用 推荐稀释比
IHC-P1:10 - 1:50
WB1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Human liver

属性

形式 Liquid
纯化 Purification with Protein A and immunogen peptide.
缓冲液 PBS and 0.09% (W/V) Sodium azide.
抗菌剂 0.09% (W/V) Sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 5009 Human OTC

Swiss-port # P00480 Human Ornithine carbamoyltransferase, mitochondrial

基因名称 OTC
全名 ornithine carbamoyltransferase
背景介绍 This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq, Jul 2008]
细胞定位 Mitochondrion matrix. [UniProt]
预测分子量 40 kDa
翻译后修饰 Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. [UniProt]

检测图片 (2) Click the Picture to Zoom In

  • ARG58999 anti-OTC / Ornithine Carbamoyltransferase antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human hepatoarcinoma stained with ARG58999 anti-OTC / Ornithine Carbamoyltransferase antibody.

  • ARG58999 anti-OTC / Ornithine Carbamoyltransferase antibody WB image

    Western blot: 20 µg of Human liver lysate stained with ARG58999 anti-OTC / Ornithine Carbamoyltransferase antibody at 1:1000 dilution.