ARG45618

anti-OS9 antibody

anti-OS9 antibody for ICC/IF,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes OS9
反应物种 Hu, Ms, Rat
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 OS9
抗原物种 Human
抗原 Recombinant protein containing to human OS9.
偶联标记 Un-conjugated
別名 OS9; OS9 Endoplasmic Reticulum Lectin; ERLEC2; OS-9; Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin; Endoplasmic Reticulum Lectin 2; Amplified In Osteosarcoma 9; Protein OS-9; Erlectin 2; Osteosarcoma Amplified 9, Endoplasmic Reticulum Associated Protein

应用说明

应用建议
应用 推荐稀释比
ICC/IF5 μg/ml
WB0.25-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified
缓冲液 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 10956 Human OS9

GeneID: 216440 Mouse OS9

GeneID: 362891 Rat OS9

基因名称 OS9
全名 OS9 Endoplasmic Reticulum Lectin
背景介绍 This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
生物功能 Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4. [UniProt]
细胞定位 Endoplasmic reticulum. [UniProt]
预测分子量 76 kDa
翻译后修饰 Disulfide bond; Glycoprotein. [UniProt]

检测图片 (4) Click the Picture to Zoom In

  • ARG45618 anti-OS9 antibody ICC/IF image

    Immunofluorescence: SiHa stained with ARG45618 anti-OS9 antibody at 5 μg/ml dilution.

  • ARG45618 anti-OS9 antibody WB image

    Western blot: Hela stained with ARG45618 anti-OS9 antibody at 0.5 μg/ml dilution.

  • ARG45618 anti-OS9 antibody WB image

    Western blot: Rat pancreas stained with ARG45618 anti-OS9 antibody at 0.5 μg/ml dilution.

  • ARG45618 anti-OS9 antibody WB image

    Western blot: Mouse pancreas stained with ARG45618 anti-OS9 antibody at 0.5 μg/ml dilution.