ARG45618
anti-OS9 antibody
anti-OS9 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
产品描述 | Rabbit Polyclonal antibody recognizes OS9 |
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反应物种 | Hu, Ms, Rat |
应用 | ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | OS9 |
抗原物种 | Human |
抗原 | Recombinant protein containing to human OS9. |
偶联标记 | Un-conjugated |
別名 | OS9; OS9 Endoplasmic Reticulum Lectin; ERLEC2; OS-9; Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin; Endoplasmic Reticulum Lectin 2; Amplified In Osteosarcoma 9; Protein OS-9; Erlectin 2; Osteosarcoma Amplified 9, Endoplasmic Reticulum Associated Protein |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purified |
缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | OS9 |
全名 | OS9 Endoplasmic Reticulum Lectin |
背景介绍 | This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
生物功能 | Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4. [UniProt] |
细胞定位 | Endoplasmic reticulum. [UniProt] |
预测分子量 | 76 kDa |
翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45618 anti-OS9 antibody ICC/IF image
Immunofluorescence: SiHa stained with ARG45618 anti-OS9 antibody at 5 μg/ml dilution.
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ARG45618 anti-OS9 antibody WB image
Western blot: Hela stained with ARG45618 anti-OS9 antibody at 0.5 μg/ml dilution.
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ARG45618 anti-OS9 antibody WB image
Western blot: Rat pancreas stained with ARG45618 anti-OS9 antibody at 0.5 μg/ml dilution.
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ARG45618 anti-OS9 antibody WB image
Western blot: Mouse pancreas stained with ARG45618 anti-OS9 antibody at 0.5 μg/ml dilution.